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Oral Dual Androgen Receptor Ligand-Directed Degrader and Antagonist as Investigational Treatment for Metastatic Castration-Resistant Prostate Cancer

Oral Dual Androgen Receptor Ligand-Directed Degrader and Antagonist as Investigational Treatment for Metastatic Castration-Resistant Prostate Cancer1

​BMS-986365 clinical trial (rechARge trial, CA071-1000) is currently open for enrollment

Find Out More See how BMS-986365 works in mCRPC​

Explore BMS-986365 in mCRPC Trial ​

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Reference(s)

  1. Rathkopf DE, Patel MR, Choudhury AD, Rasco D, Lakhani N, Hawley JE, Srinivas S, Aparicio A, Narayan V, Runcie KD, Emamekhoo H, Reichert ZR, Nguyen MH, Wells AL, Kandimalla R, Liu C, Suryawanshi S, Han J, Wu J, Arora VK, Pourdehnad M, Armstrong AJ. Safety and clinical activity of BMS-986365 (CC-94676), a dual androgen receptor ligand-directed degrader and antagonist, in heavily pretreated patients with metastatic castration-resistant prostate cancer. Ann Oncol. 2025 Jan;36(1):76-88. doi: 10.1016/j.annonc.2024.09.005. Epub 2024 Sep 16. PMID: 39293515.