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Phase 3
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18+Age Range
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TIGOS Study Information
Learn more about the TIGOS / CA245-0001 study and study procedures
Recruiting
TIGOS is a randomized, double-blind, Phase 3 clinical trial that is testing an investigational drug called BMS-986489. This clinical trial aims to see how safe and effective BMS-986489 is at treating patients with Extensive-stage SCLC. Participants will receive either BMS-986489 in combination with chemotherapy induction followed by BMS-986489 maintenance, or atezolizumab in combination with chemotherapy induction followed by atezolizumab maintenance.
Download and print the details of this study to bring to your doctor.
Patients who are 18 years or older.
Has confirmed Extensive-stage SCLC.
Can receive platinum-based chemotherapy and a PD-L1-based regimen.
Imaging has shown at least one tumor outside of the central nervous system.
*There are other requirements for taking part in this clinical trial which the study staff can explain to you. Talk to your doctor or reach out to your nearest study site using the location finder.
BMS-986489 is an investigational drug being tested to treat Small Cell lung cancer (SCLC).It combines two different types of therapies:
By combining these two different ways of working, BMS-986489 is designed to give the immune system a better chance of fighting SCLC.
BMS-986012 makes Tumor Cells findable. Nivolumab ‘Turns On’ your Immune cells1
Reference: 1. Ponath P et al. Clin Cancer Res. 2018 Oct 15;24(20):5178-89
BMS-986489 is an investigational treatment that is being used only in clinical studies that are testing its safety and effectiveness in patients with ES-SCLC.
The study is divided in three main periods: screening, treatment, and follow-up. Talk to your doctor if you are interested in joining the study. Together, you can decide if participating may be the right choice.
Step #1 - The Screening Phase
Step #2 - The Treatment Phase
Step #3 - The Follow-up Period
Talk to your doctor if you’re interested in joining the TIGOS Study. It is important for you to understand all your options before deciding what is right for you. Here are some questions you may want to ask your doctor:
Resources are also available for your healthcare team at AtigoStudyHCP.com >